GANsDTA: Predicting Drug-Target Binding Affinity Using GANs
نویسندگان
چکیده
منابع مشابه
Predicting an Aptamer’s Target Binding Affinity Using its Nucleotide Sequence
Modern molecular and cellular biology depends on markers that can very selectively bind to a target molecule. Unfortunately, the process of finding such a marker is generally slow, through trial and error, and often in vivo. Aptamers (short nucleotide sequences) are a promising type of marker that can be generated and evaluated synthetically. Currently, the process of aptamer selection involves...
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Computational prediction of the interaction between drugs and targets is a standing challenge in the field of drug discovery. A number of rather accurate predictions were reported for various binary drug-target benchmark datasets. However, a notable drawback of a binary representation of interaction data is that missing endpoints for non-interacting drug-target pairs are not differentiated from...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2020
ISSN: 1664-8021
DOI: 10.3389/fgene.2019.01243